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Article

Modern cancer epidemiological research: genetic polymorphisms and environment.

Revista de saude publica - 1 Jun 2005

Wünsch Filho Victor, Zago Marco A

Abstract excerpt

Individual cancer susceptibility seems to be related to factors such as changes in oncogenes and tumor suppressor genes expression, and differences in the action of metabolic enzymes and DNA repair regulated by specific genes. Epidemiological studies on genetic polymorphisms of human xenobiotics metabolizing enzymes and cancer have revealed low relative risks. Research considering genetic polymorphisms prevalence...

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PMID: 15997328
DOI: 10.1590/s0034-89102005000300023

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