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Article

GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming.

The EMBO journal - 15 Dec 2000

Toulmé F, Mosrin-Huaman C, Sparkowski J, Das A, Leng M, Rahmouni A R

Abstract excerpt

The GreA and GreB proteins of Escherichia coli show a multitude of effects on transcription elongation in vitro, yet their physiological functions are poorly understood. Here, we investigated whether and how these factors influence lateral oscillations of RNA polymerase (RNAP) in vivo, observed at a protein readblock. When RNAP is stalled within an (ATC/TAG)(n) sequence, it appears to oscillate between an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11118220
DOI: 10.1093/emboj/19.24.6853
PMCID: PMC305891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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