Article
Transcription factor GreA contributes to resolving promoter-proximal pausing of RNA polymerase in Bacillus subtilis cells.
Journal of bacteriology - 1 Jun 2011
Kusuya Yoko, Kurokawa Ken, Ishikawa Shu, Ogasawara Naotake, Oshima Taku
Abstract excerpt
Bacterial Gre factors associate with RNA polymerase (RNAP) and stimulate intrinsic cleavage of the nascent transcript at the active site of RNAP. Biochemical and genetic studies to date have shown that Escherichia coli Gre factors prevent transcriptional arrest during elongation and enhance transcription fidelity. Furthermore, Gre factors participate in the stimulation of promoter escape and the suppression of...
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