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Article

The detection of p53 gene mutation using a microdissection technique in primary intracranial germ cell tumors.

International journal of oncology - 1 Jan 2001

Kim S K, Cho B K, Paek S H, Hong S J, Kim H S, Hong S Y, Choe G, Chi J G, Nam D H, Wang K C

Abstract excerpt

Using a microdissection technique, the contribution of the p53 mutation to tumorigenesis and prognosis in each histological subtype of the intracranial germ cell tumors (GCTs) was evaluated. Nineteen patients had primary intracranial GCTs, including 4 germinomas (GEs), 4 teratomas (TEs), 1 mixed tumor of GE and TE, and 10 mixed GCTs containing non-germinomatous malignant germ cell tumors (NG-MGCTs). After...

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PMID: 11115546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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