Article
Molecular analysis for p53 and mdm2 in intracranial germ cell tumors.
Acta neuropathologica - 1 Jan 2000
Iwato M, Tachibana O, Tohma Y, Nitta H, Hayashi Y, Yamashita J
Abstract excerpt
Intracranial germ cell tumors (ICGTs) are uncommon neoplasms. The histological appearance of ICGTs is indistinguishable from that of the usual testicular germ cell tumors (TGTs). Recently, several reports have associated molecular abnormalities of p53 and mdm2 in TGTs with their malignancies. However, whether ICGTs are associated with molecular abnormalities is still unknown. We analyzed a series of 16 ICGTs for...
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