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Article

Regulation of Cdc42 GTPase activity in the formation of hyphae in Candida albicans.

Molecular biology of the cell - 1 Jan 2007

Court Helen, Sudbery Peter

Abstract excerpt

The human fungal pathogen Candida albicans can switch between yeast, pseudohyphal, and hyphal morphologies. To investigate whether the distinctive characteristics of hyphae are due to increased activity of the Cdc42 GTPase, strains lacking negative regulators of Cdc42 were constructed. Unexpectedly, the deletion of the Cdc42 Rho guanine dissociation inhibitor RDI1 resulted in reduced rather than enhanced...

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Identifiers

PMID: 17093060
DOI: 10.1091/mbc.e06-05-0411
PMCID: PMC1751335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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