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Article

CDC42 is required for polarized growth in human pathogen Candida albicans.

Eukaryotic cell - 1 Feb 2002

Ushinsky Sophia C, Harcus Doreen, Ash Josee, Dignard Daniel, Marcil Anne, Morchhauser Joachim, Thomas David Y, Whiteway Malcolm, Leberer Ekkehard

Abstract excerpt

Cdc42p is a member of the RAS superfamily of GTPases and plays an essential role in polarized growth in many eukaryotic cells. We cloned the Candida albicans CaCDC42 by functional complementation in Saccharomyces cerevisiae and analyzed its function in C. albicans. A double deletion of CaCDC42 was made in a C. albicans strain containing CaCDC42 under the control of the PCK1 promoter. When expression of the...

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Source

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Identifiers

PMID: 12455975
DOI: 10.1128/EC.1.1.95-104.2002
PMCID: PMC118047

Genes

PCK1
CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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