Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae.

Cell - 27 Jun 1997

Roberts R L, Mösch H U, Fink G R

Abstract excerpt

14-3-3 proteins are highly conserved ubiquitous proteins whose explicit functions have remained elusive. Here, we show that the S. cerevisiae 14-3-3 homologs BMH1 and BMH2 are not essential for viability or mating MAPK cascade signaling, but they are essential for pseudohyphal-development MAPK cascade signaling and other processes. Activated alleles of RAS2 and CDC42 induce pseudohyphal development and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biological Evolution
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Molecular Sequence Data

Share to Mutagenesis

Share to Phenotype

Share to Recombinant Proteins

Source

Identifiers

PMID: 9215628
DOI: 10.1016/s0092-8674(00)80293-7

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae.PMID 9215628Read ↗

Hsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway.Semantic proximity Read ↗

New Features Surrounding the Cdc42-Ste20 Module that Regulates MAP Kinase Signaling in YeastSemantic proximity Read ↗

The Candida albicans 14-3-3 gene, BMH1, is essential for growth.Semantic proximity Read ↗

Large-Scale Analysis of Kinase Signaling in Yeast Pseudohyphal Development Identifies Regulation of Ribonucleoprotein Granules.Semantic proximity Read ↗

Different domains of the essential GTPase Cdc42p required for growth and development of Saccharomyces cerevisiae.Semantic proximity Read ↗

The Complex Genetic Basis and Multilayered Regulatory Control of Yeast Pseudohyphal GrowthSemantic proximity Read ↗

Regulation of transcription by Saccharomyces cerevisiae 14-3-3 proteins.Semantic proximity Read ↗

Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression.Semantic proximity Read ↗

The GCKIII kinase Sps1 and the 14-3-3 isoforms, Bmh1 and Bmh2, cooperate to ensure proper sporulation in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast sphingolipid signaling landscape.Semantic proximity Read ↗

Modulators of MAPK pathway activity during filamentous growth in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Saccharomyces cerevisiae 14-3-3 proteins are required for the G1/S transition, actin cytoskeleton organization and cell wall integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.