Article
DNA replication defects delay cell division and disrupt cell polarity in early Caenorhabditis elegans embryos.
Developmental biology - 15 Dec 2000
Encalada S E, Martin P R, Phillips J B, Lyczak R, Hamill D R, Swan K A, Bowerman B
Abstract excerpt
In early Caenorhabditis elegans embryos, asymmetric cell divisions produce descendants with asynchronous cell cycle times. To investigate the relationship between cell cycle regulation and pattern formation, we have identified a collection of embryonic-lethal mutants in which cell divisions are delayed and cell fate patterns are abnormal. In div (for division delayed) mutant embryos, embryonic cell divisions are...
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