Article
Drosophila embryonic cell-cycle mutants.
G3 (Bethesda, Md.) - 3 Oct 2013
Unhavaithaya Yingdee, Park Eugenia A, Royzman Irena, Orr-Weaver Terry L
Abstract excerpt
Nearly all cell division mutants in Drosophila were recovered in late larval/pupal lethal screens, with less than 10 embryonic lethal mutants identified, because larval development occurs without a requirement for cell division. Only cells in the nervous system and the imaginal cells that generate the adult body divide during larval stages, with larval tissues growing by increasing ploidy rather than cell number....
Topics
- Animals
- Cyclin E
- Drosophila
- Drosophila Proteins
- GTPase-Activating Proteins
- Larva
- Microtubule-Associated Proteins
- Mutation
