Article
The Caenorhabditis elegans gene ham-1 regulates daughter cell size asymmetry primarily in divisions that produce a small anterior daughter cell.
PloS one - 1 Jan 2018
Teuliere Jerome, Kovacevic Ismar, Bao Zhirong, Garriga Gian
Abstract excerpt
C. elegans cell divisions that produce an apoptotic daughter cell exhibit Daughter Cell Size Asymmetry (DCSA), producing a larger surviving daughter cell and a smaller daughter cell fated to die. Genetic screens for mutants with defects in apoptosis identified several genes that are also required for the ability of these divisions to produce daughter cells that differ in size. One of these genes, ham-1, encodes a...
Topics
- Animals
- Apoptosis
- Asymmetric Cell Division
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Division
- Cell Lineage
- Cell Size
- Cell Survival
- Models, Biological
- Mutation
- Nerve Tissue Proteins
- Neurons
- Phenotype