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Article

Reciprocal asymmetry of SYS-1/β-catenin and POP-1/TCF controls asymmetric divisions in <i>Caenorhabditis elegans</i>

12 Feb 2007

Abstract excerpt

beta-Catenins are conserved regulators of metazoan development that function with TCF DNA-binding proteins to activate transcription. In Caenorhabditis elegans, SYS-1/beta-catenin and POP-1/TCF regulate several asymmetric divisions, including that of the somatic gonadal precursor cell (SGP). In the distal but not the proximal SGP daughter, SYS-1/beta-catenin and POP-1/TCF transcriptionally activate ceh-22 to...

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PMID: 17296929
DOI: 10.1073/pnas.0611507104

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