Article
Transcriptional Activators Differ in Their Responses to Overexpression of TATA-Box-Binding Protein
1 Mar 1995
Abstract excerpt
We investigated how overexpression of human TATA-box-binding protein (TBP) affects the action of estrogen receptor (ER) and compared the response with that of other activators. When ER activates a simple promoter, consisting of a response element and either the collagenase or tk TATA box, TBP overexpression potentiates transcription. TBP potentiates only estrogen-induced and not basal transcription and does so...
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