Article
Transcriptional repression of the mouse wee1 gene by TBP-related factor 2.
Biochemical and biophysical research communications - 5 Jan 2007
Tanaka Yuji, Nanba Yasu-aki, Park Kyoung-ae, Mabuchi Tomoko, Suenaga Yusuke, Shiraishi Seiji, Shimada Miho, Nakadai Tomoyoshi, Tamura Taka-aki
Abstract excerpt
TBP-related factor 2 (TRF2), one of the TBP family proteins, is involved in various cellular functions through its transcription stimulation activity. We previously reported that TRF2 is involved in reduction of wee1 mRNA in genotoxin-treated chicken cells. In this study, we investigated the role of TRF2 in wee1 gene expression. It was found that wee1 mRNA was decreased in hydroxyurea-treated NIH3T3 cells. Mouse...
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