Article
DNA bending is an important component of site-specific recognition by the TATA binding protein.
Journal of molecular biology - 21 Jul 1995
Starr D B, Hoopes B C, Hawley D K
Abstract excerpt
We have used gel electrophoretic methods to analyze the extent, location and direction of the DNA bend induced by the TATA binding protein (TBP) upon binding to a consensus TATA box sequence. Our observations were consistent with the proposed models for the X-ray crystal structure of the TBP-TATA...
Topics
- Base Composition
- Base Sequence
- Binding Sites
- DNA
- DNA-Binding Proteins
- Deoxyribonuclease I
- Electrophoresis, Polyacrylamide Gel
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- TATA Box
- TATA-Box Binding Protein
- Transcription Factors
- Transcription, Genetic