Article
Effect of apolipoprotein A-IV genotype and dietary fat on cholesterol absorption in humans.
Journal of lipid research - 1 Dec 2000
Weinberg R B, Geissinger B W, Kasala K, Hockey K J, Terry J G, Easter L, Crouse J R
Abstract excerpt
We investigated the effect of the A-IV-2 allele, which encodes a Q360H substitution in apolipoprotein (apo) A-IV, and dietary fat on cholesterol absorption in humans. In three separate studies we compared fractional intestinal cholesterol absorption between groups of subjects heterozygous for the A-IV-2 allele (1/2) and homozygous for the common allele (1/1) receiving high cholesterol ( approximately 800 mg/day)...
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