Article
Effect of the apolipoprotein A-IV Q360H polymorphism on postprandial plasma triglyceride clearance.
Journal of lipid research - 1 Feb 2001
Hockey K J, Anderson R A, Cook V R, Hantgan R R, Weinberg R B
Abstract excerpt
Apolipoprotein (apo)A-IV is synthesized in the small intestine during fat absorption and is incorporated onto the surface of nascent chylomicrons. In circulation, apoA-IV is displaced from the chylomicron surface by high density lipoprotein-associated C and E apolipoproteins; this exchange is critical for activation of lipoprotein lipase and chylomicron remnant clearance. The variant allele A-IV-2 encodes a Q360H...
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