Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele.

doi:10.1056/NEJM199409153311104

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Article

Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele.

The New England journal of medicine - 15 Sept 1994

McCombs R J, Marcadis D E, Ellis J, Weinberg R B

Abstract excerpt

BACKGROUND: Previous studies have suggested that the variant apolipoprotein (apo) allele apo A-IV-2 may influence the response of the plasma cholesterol concentration to dietary cholesterol. METHODS: We measured plasma lipids and lipoproteins in 11 subjects who were heterozygous for the apo A-IV-...

Topics

Adult
Alleles
Apolipoprotein A-I
Cholesterol
Cholesterol, Dietary
Cholesterol, HDL
Cholesterol, LDL
Female
Heterozygote
Humans
Hypercholesterolemia
Male
Triglycerides

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