Article
Effect of 347-serine mutation in apoprotein A-IV on plasma LDL cholesterol response to dietary fat.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1997
Jansen S, Lopez-Miranda J, Salas J, Ordovas J M, Castro P, Marin C, Ostos M A, Lopez-Segura F, Jimenez-Pereperez J A, Blanco A, Perez-Jimenez F
Abstract excerpt
Lipid response to dietary fat and cholesterol is, to a large extent, genetically controlled. Apoprotein (apo) A-IV has been related to fat absorption and to the activation of some of the enzymes involved in lipid metabolism. One mutation has been described in the apo A-IV gene that causes substitution of Ser for Thr at position 347. To study the influence of this mutation on the plasma LDL cholesterol (LDL-C)...
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