Article
Genetic variation at the apoA-IV gene locus and response to diet in familial hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1998
Carmena-Ramón R, Ascaso J F, Real J T, Ordovas J M, Carmena R
Abstract excerpt
Plasma lipid response to dietary fat and cholesterol is, in part, genetically controlled. The apolipoprotein A-IV (apoA-IV protein; APOA4, gene) has been shown to influence the response to dietary changes in normolipidemic individuals. The response to diet in subjects with familial hypercholesterolemia (FH) is also variable, and no studies are available on the influence of APOA4 mutations on dietary response in...
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