Genetic variation at the apoA-IV gene locus and response to diet in familial hypercholesterolemia.

doi:10.1161/01.atv.18.8.1266

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Article

Genetic variation at the apoA-IV gene locus and response to diet in familial hypercholesterolemia.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 1998

Carmena-Ramón R, Ascaso J F, Real J T, Ordovas J M, Carmena R

Abstract excerpt

Plasma lipid response to dietary fat and cholesterol is, in part, genetically controlled. The apolipoprotein A-IV (apoA-IV protein; APOA4, gene) has been shown to influence the response to dietary changes in normolipidemic individuals. The response to diet in subjects with familial hypercholester...

Topics

Adult
Alleles
Analysis of Variance
Apolipoproteins A
Dietary Fats
Female
Genetic Variation
Genotype
Heterozygote
Humans
Hypercholesterolemia
Lipids
Male
Middle Aged
Mutation
Statistics, Nonparametric

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