Article
Phagocyte oxidants and nitric oxide in cystic fibrosis: new therapeutic targets?
Current opinion in pulmonary medicine - 1 Nov 2000
van der Vliet A, Cross C E
Abstract excerpt
Chronic persistent respiratory tract (RT) infection and overly exuberant activation of host inflammatory-immune processes represent the paramount pathobiologic consequences of cystic fibrosis (CF). The host inflammatory-immune system activation includes the production of reactive oxygen species (ROS) and nitric oxide (NO*), which are helpful in RT antimicrobial defenses but under conditions of excess are believed...
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