Article
A Novel Host Defense System of Airways is Defective in Cystic Fibrosis
2 Nov 2006
Abstract excerpt
RATIONALE: The respiratory tract is constantly exposed to airborne microorganisms. Nevertheless, normal airways remain sterile without recruiting phagocytes. This innate immune activity has been attributed to mucociliary clearance and antimicrobial polypeptides of airway surface liquid. Defective airway immunity characterizes cystic fibrosis (CF), a disease caused by mutations in the CF transmembrane conductance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
