Cystic fibrosis and the innate immune system: therapeutic implications.

Abstract excerpt

Cystic Fibrosis (CF), the most common autosomal lethal disorder in Caucasians, is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Although CF is multi-organ disease, the lung pathology is the chief cause of morbidity and mortality of CF patients. The hallmarks of CF lung disease are respiratory infection by opportunistic pathogens and a deranged inflammatory response. However,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ceramides
• Share to Cystic Fibrosis Transmembrane Conductance Regulator
• Share to Glutathione