Article
Oxidative stress and free radicals in COPD--implications and relevance for treatment.
International journal of chronic obstructive pulmonary disease - 1 Jan 2014
Domej Wolfgang, Oettl Karl, Renner Wilfried
Abstract excerpt
Oxidative stress occurs when free radicals and other reactive species overwhelm the availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and their counterpart antioxidant agents are essential for physiological signaling and host defense, as well as for the evolution and persistence of inflammation. When their normal steady state is disturbed, imbalances between oxidants and...
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