Article
Mechanisms of the noxious inflammatory cycle in cystic fibrosis.
Respiratory research - 13 Mar 2009
Rottner Mathilde, Freyssinet Jean-Marie, Martínez M Carmen
Abstract excerpt
Multiple evidences indicate that inflammation is an event occurring prior to infection in patients with cystic fibrosis. The self-perpetuating inflammatory cycle may play a pathogenic part in this disease. The role of the NF-kappaB pathway in enhanced production of inflammatory mediators is well...
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