Glutamine and tetrapeptide repeat variations affect the biological activity of different mouse interleukin-2 alleles.

doi:10.1002/eji.1830260802

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Article

Glutamine and tetrapeptide repeat variations affect the biological activity of different mouse interleukin-2 alleles.

European journal of immunology - 1 Aug 1996

Matesanz F, Alcina A

Abstract excerpt

Mouse interleukin-2 (IL-2) was thought to be encoded by a single allele. We have recently described N-terminal differences in five IL-2 molecules from nine mouse strains analyzed (Matesanz, F., Alcina, A. and Pellicer, A., Immunogenetics 1993. 38: 300). In this study, we isolated and sequenced th...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cell Division
Cells, Cultured
Glutamine
Humans
Interleukin-2
Mice
Mice, Mutant Strains
Molecular Sequence Data
Oligopeptides
Recombinant Proteins
Repetitive Sequences, Nucleic Acid

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