Article
Establishment of the paternal methylation imprint of the human H19 and MEST/PEG1 genes during spermatogenesis
1 Sept 2000
Abstract excerpt
Parental-specific epigenetic modifications are imprinted on a subset of genes in the mammalian genome during germ cell maturation. However, the precise timing of their establishment remains to be determined. Methylation of CpG dinucleotides has been shown to be a part of the parental imprint. We have examined how the methylation pattern characteristic of the paternal allele in germ cells are established during...
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