Article
Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 1999
Chen C R, Li Y C, Chen J, Hou M C, Papadaki P, Chang E C
Abstract excerpt
In fission yeast, Scd1/Ral1 is a putative guanine nucleotide exchange factor for Cdc42sp and also acts as a Ras1 effector necessary for the regulation of cytoskeleton organization. In this study, we have characterized a protein, Moe1, that binds directly to Scd1. A moe1 null (Delta) mutant exhibi...
Topics
- Carrier Proteins
- Cell Cycle Proteins
- Cell Division
- Cloning, Molecular
- Eukaryotic Initiation Factors
- Evolution, Molecular
- Fungal Proteins
- Green Fluorescent Proteins
- Guanine Nucleotide Exchange Factors
- Humans
- Luminescent Proteins
- Microscopy, Fluorescence
- Microtubules
- Molecular Sequence Data