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Article

The interaction between Ran and NTF2 is required for cell cycle progression.

Molecular biology of the cell - 1 Aug 2000

Quimby B B, Wilson C A, Corbett A H

Abstract excerpt

The small GTPase Ran is required for the trafficking of macromolecules into and out of the nucleus. Ran also has been implicated in cell cycle control, specifically in mitotic spindle assembly. In interphase cells, Ran is predominately nuclear and thought to be GTP bound, but it is also present in the cytoplasm, probably in the GDP-bound state. Nuclear transport factor 2 (NTF2) has been shown to import RanGDP...

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Identifiers

PMID: 10930458
DOI: 10.1091/mbc.11.8.2617
PMCID: PMC14944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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