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Article

The Ran GTPase cycle is required for yeast nuclear pore complex assembly.

The Journal of cell biology - 31 Mar 2003

Ryan Kathryn J, McCaffery J Michael, Wente Susan R

Abstract excerpt

Here, we report the first evidence that the Ran GTPase cycle is required for nuclear pore complex (NPC) assembly. Using a genetic approach, factors required for NPC assembly were identified in Saccharomyces cerevisiae. Four mutant complementation groups were characterized that correspond to respective mutations in genes encoding Ran (gsp1), and essential Ran regulatory factors Ran GTPase-activating protein...

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Identifiers

PMID: 12654904
DOI: 10.1083/jcb.200209116
PMCID: PMC2172763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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