Article
Absence of linkage between inflammatory bowel disease and selected loci on chromosomes 3, 7, 12, and 16.
Gastroenterology - 1 Nov 1998
Rioux J D, Daly M J, Green T, Stone V, Lander E S, Hudson T J, Steinhart A H, Bull S, Cohen Z, Greenberg G, Griffiths A, McLeod R, Silverberg M, Williams C N, Siminovitch K A
Abstract excerpt
BACKGROUND & AIMS: Linkage data derived from genome-wide scans of inflammatory bowel disease (IBD) sibling-pair families have identified 4 loci on chromosomes 3, 7, 12, and 16 as potential sites for IBD susceptibility genes. The aim of this study was to investigate whether linkage analysis of ano...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 16
- Chromosomes, Human, Pair 3
- Chromosomes, Human, Pair 7
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Inflammatory Bowel Diseases
- Lod Score
- Microsatellite Repeats
