The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease.

doi:10.1007/s003840050173

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Article

The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease.

International journal of colorectal disease - 1 Jan 1998

Hampe J, Hermann B, Bridger S, MacPherson A J, Mathew C G, Schreiber S

Abstract excerpt

Epidemiological and genome-wide linkage analyses have provided firm evidence for a genetic component in the pathogenesis of inflammatory bowel disease. The linkage regions on chromosomes 12 and 16 have been replicated in several independent samples. These represent the best positional evidence in...

Topics

Base Sequence
Chromosomes, Human, Pair 12
Colitis, Ulcerative
Crohn Disease
Female
Genetic Predisposition to Disease
Humans
Inflammatory Bowel Diseases
Interferon-gamma
Lod Score
Male
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9870173
DOI: 10.1007/s003840050173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9870173-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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