Article
Structural analysis of human immunodeficiency virus type 1 Gag protein interactions, using cysteine-specific reagents.
Journal of virology - 1 Aug 1996
McDermott J, Farrell L, Ross R, Barklis E
Abstract excerpt
We have examined structural interactions of Gag proteins in human immunodeficiency virus type 1 (HIV-1) particles by utilizing cysteine mutagenesis and cysteine-specific modifying reagents. In immature protease-minus but otherwise wild-type (wt) particles, precursor Pr55Gag proteins did not form intermolecular cystines naturally but could be cross-linked at cysteines, and cross-linking appeared to occur across...
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