Article
Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth.
The Journal of cell biology - 30 Oct 2000
Dunn S E, Chin E R, Michel R N
Abstract excerpt
Calcineurin-dependent pathways have been implicated in the hypertrophic response of skeletal muscle to functional overload (OV) (Dunn, S.E., J.L. Burns, and R.N. Michel. 1999. J. Biol. Chem. 274:21908-21912). Here we show that skeletal muscles overexpressing an activated form of calcineurin (CnA*) exhibit a phenotype indistinguishable from wild-type counterparts under normal weightbearing conditions and respond...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
