Article
Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling.
Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2003
Chakkalakal Joe V, Stocksley Mark A, Harrison Mary-Ann, Angus Lindsay M, Deschenes-Furry Julie, St-Pierre Simon, Megeney Lynn A, Chin Eva R, Michel Robin N, Jasmin Bernard J
Abstract excerpt
Utrophin levels have recently been shown to be more abundant in slow vs. fast muscles, but the nature of the molecular events underlying this difference remains to be fully elucidated. Here, we determined whether this difference is due to the expression of utrophin A or B, and examined whether transcriptional regulatory mechanisms are also involved. Immunofluorescence experiments revealed that slower fibers...
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