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Article

Calcineurin activation influences muscle phenotype in a muscle-specific fashion.

BMC cell biology - 28 Jul 2004

Talmadge Robert J, Otis Jeffrey S, Rittler Matthew R, Garcia Nicole D, Spencer Shelly R, Lees Simon J, Naya Francisco J

Abstract excerpt

BACKGROUND: The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of physiological signals (free cytosolic Ca2+) into molecular signals that influence the expression of phenotype-specific genes in skeletal muscle. In the present study we address the role of calcineurin in mediating adaptations in myosin heavy chain...

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Source

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Identifiers

PMID: 15282035
DOI: 10.1186/1471-2121-5-28
PMCID: PMC509416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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