Article
The A19G polymorphism in the 5' untranslated region of the human obese gene does not affect leptin levels in severely obese patients.
The Journal of clinical endocrinology and metabolism - 1 Oct 2000
Lucantoni R, Ponti E, Berselli M E, Savia G, Minocci A, Calò G, de Medici C, Liuzzi A, Di Blasio A M
Abstract excerpt
Recently, the presence of different polymorphisms in the regulatory region of the ob gene has been associated with variations in leptin levels. However, the results of these studies are still contradictory. The aim of the present investigation was to evaluate the presence of the A19G polymorphism in an Italian population of obese patients and to verify its association with leptin levels and anthropometric,...
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