Article
Variants in the human beta 1-, beta 2-, and beta 3-adrenergic receptor genes are not associated with morbid obesity in children and adolescents.
Diabetes, obesity & metabolism - 1 Nov 2004
Tafel J, Branscheid I, Skwarna B, Schlimme M, Morcos M, Algenstaedt P, Hinney A, Hebebrand J, Nawroth P, Hamann A
Abstract excerpt
AIM: beta-adrenergic receptors (beta-ARs) are of key importance for the regulation of lipolysis and thermogenesis by catecholamines. Genetic defects in expression or function of beta(1)- beta(2)- and/or beta(3)-AR could affect energy homeostasis and predispose an individual towards the development of obesity. We therefore investigated the possible association of polymorphisms in the beta-adrenergic receptor genes...
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