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Article

Gene polymorphisms and increased DNA damage in morbidly obese women.

Mutation research - 1 Jun 2015

Luperini B C O, Almeida D C, Porto M P, Marcondes J P C, Prado R P, Rasera I, Oliveira M R M, Salvadori D M F

Abstract excerpt

Obesity is characterized by increased adipose tissue mass resulting from a chronic imbalance between energy intake and expenditure. Furthermore, there is a clearly defined relationship among fat mass expansion, chronic low-grade systemic inflammation and reactive oxygen species (ROS) generation; leading to ROS-related pathological events. In the past years, genome-wide association studies have generated...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26255942
DOI: 10.1016/j.mrfmmm.2015.01.004

Genes

FTO
GHRL
GHSR
LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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