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Article

Identification of functional domains and dominant negative mutations in vertebrate telomerase RNA using an in vivo reconstitution system.

The Journal of biological chemistry - 23 Feb 2001

Martin-Rivera L, Blasco M A

Abstract excerpt

The telomerase holoenzyme consists of two essential components, a reverse transcriptase, TERT (telomerase reverse transcriptase), and an RNA molecule, TR (telomerase RNA, also known as TERC), that contains the template for the synthesis of new telomeric repeats. Telomerase RNA has been isolated from 32 different vertebrates, and a common secondary structure has been proposed (Chen, J.-L., Blasco, M. A., and...

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Identifiers

PMID: 11056167
DOI: 10.1074/jbc.M008419200

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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