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Article

The unmasking of telomerase.

Structure (London, England : 1993) - 1 Nov 2006

Legassie Jason D, Jarstfer Michael B

Abstract excerpt

Telomerase is a ribonucleoprotein complex that reverse transcribes a portion of its RNA subunit during the synthesis of G-rich DNA at the 3' end of each chromosome in most eukaryotes. This activity compensates for the inability of the normal DNA replication machinery to fully replicate chromosome termini. The roles of telomerase in cellular immortality and tumor biology have catalyzed a significant interest in...

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Identifiers

PMID: 17098185
DOI: 10.1016/j.str.2006.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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