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Article

Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2000

Goepfert T M, McCarthy M, Kittrell F S, Stephens C, Ullrich R L, Brinkley B R, Medina D

Abstract excerpt

Mammary epithelial cells from p53 null mice have been shown recently to exhibit an increased risk for tumor development. Hormonal stimulation markedly increased tumor development in p53 null mammary cells. Here we demonstrate that mammary tumors arising in p53 null mammary cells are highly aneupl...

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Source

Identifiers

PMID: 11053243
DOI: 10.1096/fj.00-0165com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11053243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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