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Article

Antiprogestins inhibit growth and stimulate differentiation in the normal mammary gland.

Journal of cellular physiology - 1 Jul 1995

Li M, Spitzer E, Zschiesche W, Binas B, Parczyk K, Grosse R

Abstract excerpt

Antiprogestins possess a potent antitumor activity in hormone-dependent experimental breast cancer models. Though the underlying mechanism is not clear, induction of functional differentiation seems to be a major event. This study attempts to test directly for antiproliferative and differentiation promoting activities of antiprogestins on the normal mammary gland. To this end, whole organ cultures of mammary...

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Identifiers

PMID: 7790381
DOI: 10.1002/jcp.1041640102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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