Article
Hormonal control of p53 and chemoprevention.
Breast cancer research : BCR - 1 Jan 2002
Jerry D Joseph, Minter Lisa M, Becker Klaus A, Blackburn Anneke C
Abstract excerpt
Improvements in the detection and treatment of breast cancer have dramatically altered its clinical course and outcome. However, prevention of breast cancer remains an elusive goal. Parity, age of menarche, and age at menopause are major risk factors drawing attention to the important role of the endocrine system in determining the risk of breast cancer, while heritable breast cancer susceptibility syndromes have...
Topics
- Breast Neoplasms
- Chemoprevention
- Female
- Genes, Tumor Suppressor
- Genetic Predisposition to Disease
- Hormones
- Humans
- Tumor Suppressor Protein p53