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Article

Neural hyperplasia induced by RNA interference with m4/malpha gene activity.

Mechanisms of development - 1 Nov 2000

Nagel A C, Apidianakis Y, Wech I, Maier D, Delidakis C, Preiss A

Abstract excerpt

The E(spl) complex (E(spl)-C) contains three different classes of genes that are downstream of Notch signaling. The bHLH genes mediate the Notch signal by repressing proneural gene activity, for example during the singularization of mechanosensory organ precursor cells (SOPs). Genes of the second class, the E(spl) m4/malpha family, antagonize this process if overexpressed. Here we show that this is based on...

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PMID: 11044604
DOI: 10.1016/s0925-4773(00)00446-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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