Article
The Polyhomeotic protein induces hyperplastic tissue overgrowth through the activation of the JAK/STAT pathway.
Cell cycle (Georgetown, Tex.) - 15 Dec 2009
González Inma, Simón Rocío, Busturia Ana
Abstract excerpt
Epigenetic mechanisms controlling cellular proliferation are essential to animal development. Moreover, altered levels of expression of the epigenetic regulator proteins are associated with the development and progression of human diseases like cancer. We have studied the effects of high levels of Polyhomeotic (PH) protein, a member of the Polycomb Group (PcG), during the proliferation of the imaginal discs in...
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