Article
Persistent expression of genes of the enhancer of split complex suppresses neural development in Drosophila.
Neuron - 1 Feb 1996
Nakao K, Campos-Ortega J A
Abstract excerpt
The segregation of neural and epidermal progenitors in Drosophila requires the activity of transcription factors encoded by the proneural genes and the genes of the E(SPL)-C. Persistent expression of two genes of the E(SPL)-C suppresses neural development. Embryos exhibit conspicuous central neural hypoplasia and lack sensory organs; imaginal sensory organs are also affected. Suppression of neural development is...
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