Article
Genotype-environment interaction in transmission disequilibrium tests.
Advances in genetics - 1 Jan 2001
Eaves L J, Sullivan P
Abstract excerpt
Transmission disequilibrium tests (TDTs) provide an approach to the detection of associations between alleles at marker loci and risk of complex disorders. The logistic regression approach to TDTs proposed by Sham and Curtis (1995) is generalized to provide separate tests of the main effects of marker loci on genetic risk and genotype-environment interaction (G x E) arising because multiple alleles differ in...
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