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Article

Epidemiologic analysis of gene-environment interaction in twins.

Genetic epidemiology - 1 Jan 1994

Ottman R

Abstract excerpt

Our aim was to develop a simple method for testing gene-environment interaction in twin data ascertained through affected twins (probands), with known exposure status of both cotwins. To this end we derived formulae for two epidemiologic measures, as a function of prevalence of an exposure and genotype, and disease risk conditional on exposure and genotype: (1) relative risk of disease in exposed vs. unexposed...

Topics

Bias
Confounding Factors, Epidemiologic
Diseases in Twins
Environment
Epidemiologic Methods
Evaluation Studies as Topic
Genotype
Humans
Models, Genetic
Prevalence
Risk Factors
Twins, Dizygotic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Twins, Monozygotic

Source

Identifiers

PMID: 8013890
DOI: 10.1002/gepi.1370110108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8013890-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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