Article
Epidemiologic analysis of gene-environment interaction in twins.
Genetic epidemiology - 1 Jan 1994
Ottman R
Abstract excerpt
Our aim was to develop a simple method for testing gene-environment interaction in twin data ascertained through affected twins (probands), with known exposure status of both cotwins. To this end we derived formulae for two epidemiologic measures, as a function of prevalence of an exposure and genotype, and disease risk conditional on exposure and genotype: (1) relative risk of disease in exposed vs. unexposed...
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