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Article

Mutation in csrR global regulator reduces Streptococcus pyogenes internalization.

Microbial pathogenesis - 1 Nov 2000

Jadoun J, Sela S

Abstract excerpt

Transposon (Tn 916) mutagenesis was employed to identify genes in group A streptococcus (GAS) that are involved in bacterial internalization by epithelial cells. One mutant displayed significantly reduced internalization efficiency and was therefore selected for further characterization. The mutant harbored a single Tn 916 insertion in csr, a genetic locus encoding a two-component regulatory system. Mutations in...

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Identifiers

PMID: 11031125
DOI: 10.1006/mpat.2000.0392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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